The RAS protein acquires a mutation that prevents release of GTP. Which of the following characteristics are these cells likely to acquire?

Question

a)Self-sufficiency in growth signals
b) insensitivity to anti growth signals
c) angiogenesis
d) metastasis
e) blocking apoptosis

I believe the answer is blocking apoptosis because Mutation to the RAS protein would turn the protocogene to a oncogene making it able to survive and proliferate.

Answer 1

Hi Sra,

I took a look at some of the links and it seems that both metastasis and inhibition of apoptosis can occur. However, I still think its E since that needs to occur first before metastasis may occur? Would my reasoning be logical?