The purpose of environmental epidemiology studies is to prove that an environmental agent is the cause of a particular adverse effect.

Question

True
False

2. Which of the following is not an accurate statement about dose-response?

The NOAEL is the highest data point on the dose-response graph that produced an adverse effect.
The dose-response is used to establish causality between a compound and an effect
The bell shaped curve demonstrates individual variation in response to a particular dose
The shape and slope of the dose-response curve is extremely important in predicting the toxicity of a substance at specific dose levels.

3. The hallmark of a toxic response is that adverse effects are immediate. (Points: 3)
True
False

4. Please match the biomarker term with the appropriate item. (Points: 3)

Matching:

Answer Potential Matches:
: A biomarker for exposure 1: Levels of dioxin measured in the bloodstream.
2: The presence of the BRCA gene in a DNA sample
3: Levels of a protein which rises in the case of tissue damage

: A biomarker for effect
: A biomarker for susceptibility

5. Two chemicals are synergistic when exposure to one chemical causes a dramatic increase in the effect of another chemical.
True
False

6. An environmental health researcher who wants to determine whether people who lived in houses with high amounts of radon die at a greater rate than the general population should do a:
case control study
randomized clinical trial
dose-response study
retrospective cohort study