To find the sum of the populations of the two cities, we first need to express both populations in a compatible form before we can add them.
- The population of the first city is \(3.45 \times 10^6\).
- The population of the second city is \(1.3 \times 10^5\).
Before adding these numbers, we should convert \(1.3 \times 10^5\) to a form with the same power of 10 as \(3.45 \times 10^6\):
\[ 1.3 \times 10^5 = 0.13 \times 10^6 \]
Now, we can add the two populations:
\[ 3.45 \times 10^6 + 0.13 \times 10^6 = (3.45 + 0.13) \times 10^6 = 3.58 \times 10^6 \]
Thus, the sum of the populations of the two cities in scientific notation is:
\[ \boxed{3.58 \times 10^6} \]