To find the sum of the populations of the two cities in scientific notation, we first need to express both populations with the same exponent for easier addition.
The populations are:
- City A: \( 3.45 \times 10^6 \)
- City B: \( 1.3 \times 10^5 \)
We can convert City B's population to a similar exponent as City A's:
\[ 1.3 \times 10^5 = 0.13 \times 10^6 \]
Now we can add the two populations:
\[ 3.45 \times 10^6 + 0.13 \times 10^6 = (3.45 + 0.13) \times 10^6 = 3.58 \times 10^6 \]
Thus, the sum of the populations of the two cities in scientific notation is:
\[ \boxed{3.58 \times 10^6} \]