To categorize the mutation shown in the sequences provided, we need to compare the original DNA sequence with the mutated DNA sequence.
In the original sequence, the nucleotides are:
Original Sequence:
A T A C G G T A G C A A
T A T G C C A T C G T T
In the mutated sequence, we see the following changes:
Mutated Sequence:
A T A C G G T A G A A
T A T G C C A T C T T
Looking closely at the sequences, we can identify the following changes:
- In the first row, the original sequence has "G C" (last two bases), while the mutated sequence has "A A".
- In the second row, the original sequence has "G T" at the end, while the mutated sequence has "C T" (the original "G" has been replaced with "C", and the "T" has been replaced with "A").
Since the mutation results in a single base change (the substitution of a nucleotide) at specific positions, this type of mutation is classified as a substitution mutation.
Therefore, the correct response is: substitution mutation.
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