To find the volume of a square prism using the formula \( V = s^2 h \), where \( s \) is the length of each side of the square base and \( h \) is the height of the prism, we can substitute the given values \( s = 4 \) and \( h = 6 \).
First, calculate \( s^2 \):
\[ s^2 = 4^2 = 16 \]
Next, multiply by the height \( h \):
\[ V = s^2 h = 16 \times 6 = 96 \]
Therefore, the volume of the square prism is 96 cubic centimeters.