In the French and Indian War, which was part of the Seven Years' War, the main combatants on the two opposing sides were:
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British: The British colonies in America, along with British regular troops, were a major fighting force against the French.
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French: The French, along with their colonial troops in North America and various Native American allies, fought against the British forces.
These two groups were the primary opponents in the conflict, with the British ultimately emerging victorious, leading to significant changes in territorial claims in North America.