The “central dogma” is a supposedly firm principle that explains how genes function in cells. With the emergence of AIDS, the central dogma has come into question because of the ability of the AIDS virus to convert RNA into DNA. What is the central dogma and why has the principle come into question

Answer 1

<<The Central Dogma: DNA Encodes RNA, RNA Encodes Protein. The central dogma of molecular biology describes the flow of genetic information in cells from DNA to messenger RNA (mRNA) to protein. It states that genes specify the sequence of mRNA molecules, which in turn specify the sequence of proteins .>>
<< It doesn't really deviate from the updated central dogma. The deviation you are referring to is the transfer of information from RNA to DNA. The conventional central dogma stated that information travels unidirectionally from DNA to RNA to Proteins. Since HIV goes from RNA to DNA it is regarded a deviation. This process of going RNA to DNA is called reverse transcription.

HIV has a RNA genome. after infection, this RNA makes a complementary DNA strands. This then becomes a double-stranded DNA molecule which gets integrated into the host DNA molecule. >>