The organelle that is defective in Tay-Sachs disease is the Lysosome. In Tay-Sachs, there is a deficiency of the enzyme hexosaminidase A, which is necessary for the breakdown of certain lipids (gangliosides). As a result, these lipids accumulate in the lysosomes, leading to the symptoms associated with the disease.
Tay-Sachs is a disease that occurs when lipids accumulate in cells. This lipid accumulation occurs because of the inability of the cell to break down lipids due to the lack of function of the organelle responsible for intracellular digestion. Which organelle is defective in Tay-Sachs?
Responses
Golgi apparatus
Golgi apparatus
Lysosome
Lysosome
Ribosome
Ribosome
Mitochondrion
1 answer