summarize this Nicotine potentiates gastric aggressive factors and attenuates defensive factors; it also increases acid and pepsin secretions, gastric motility, duodenogastric reflux of bile salts, the risk of Helicobacter pylori infection, levels of free radicals, and platelet-activating factor, endothelin generation, and ...

Answer 1

Nicotine increases factors that contribute to stomach irritation and damage, such as acid and pepsin secretion, while also reducing protective factors. It can also lead to increased risk of Helicobacter pylori infection and elevated levels of free radicals and platelet-activating factor.