Summarize these topics in to brief and short

Question

1.Discuss on Nucleic acid structures and compositions.
2. De novo synthesis of purine nucleotides.
3. Degradation of purine nucleotides and associated diseases.
4. De novo synthesis of pyrimidines. 5.Disorders of pyrimidine metabolism

Answer 1

1. Nucleic acids are composed of nucleotides which consist of a sugar, phosphate group, and nitrogenous base.
2. Purine nucleotides are synthesized through de novo synthesis pathway involving multiple enzyme reactions.
3. Degradation of purine nucleotides can lead to diseases like gout and Lesch-Nyhan syndrome.
4. Pyrimidines are synthesized de novo through a pathway separate from purines.
5. Disorders of pyrimidine metabolism can result in neurological and developmental issues.