To find out how much farther Neptune is from Earth than Mars, we need to subtract the distance from Earth to Mars from the distance from Earth to Neptune.
Given:
- Distance to Mars: \( 2.25 \times 10^8 \) km
- Distance to Neptune: \( 4.3514 \times 10^9 \) km
Let's subtract the two distances:
\[ 4.3514 \times 10^9 - 2.25 \times 10^8 \]
To perform this subtraction, we need to express both numbers with the same power of 10. We can express \( 2.25 \times 10^8 \) with a power of \( 10^9 \):
\[ 2.25 \times 10^8 = 0.225 \times 10^9 \]
Now we can rewrite the subtraction:
\[ 4.3514 \times 10^9 - 0.225 \times 10^9 \]
This can be simplified to:
\[ (4.3514 - 0.225) \times 10^9 = 4.1264 \times 10^9 \]
Therefore, the distance from Earth to Neptune minus the distance from Earth to Mars is:
\[ \boxed{4.1264 \times 10^9} \text{ km} \]