The sequence you provided for the export of a protein from the cell is correct. Here’s a breakdown of the process:
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Ribosome: Proteins destined for export are initially synthesized by ribosomes. If the protein is to be secreted, it is synthesized on ribosomes that are bound to the rough endoplasmic reticulum (rough ER).
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Rough ER: The newly formed protein enters the rough ER, where it undergoes folding and may undergo modifications (such as glycosylation).
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Vesicle: The proteins are then packaged into vesicles that bud off from the rough ER, transporting them to the Golgi apparatus.
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Golgi apparatus: In the Golgi apparatus, proteins are further modified, sorted, and packaged for their final destinations, which could include export from the cell.
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Vesicle: After processing in the Golgi, the proteins are again packaged into vesicles that bud off from the Golgi apparatus.
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Cell membrane: Finally, these vesicles travel to and fuse with the cell membrane, releasing the proteins into the extracellular space.
In summary, the correct sequence of organelles for a protein being exported from the cell is: Ribosome → Rough ER → Vesicle → Golgi Apparatus → Vesicle → Cell Membrane.
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