The statement that requires a comma between adjectives is Statement 2: "Driving more than 10 hours straight can make you dangerously drowsy."
In this case, "dangerously" is an adverb modifying the adjective "drowsy," which means that Statement 2 does not require a comma between adjectives because it does not have two adjectives describing the same noun.
The correct choice based on the consideration of adjectives requiring commas is none of the statements listed require a comma between adjectives.
However, if we were looking for a statement that involves adjectives in a more direct sense, Statement 4 could be interpreted as involving a compound adjective ("short, sharp") where a comma may be warranted due to their equal weight in describing "shock."
So, among the options given, the closest one that could be seen as needing clarification around commas would be D Statement 4 only. However, note that in “short sharp shock,” the two adjectives directly modify the noun without needing a comma according to the rules of combining adjectives.
If you are strictly looking for the one that fits the typical rule of needing commas for separate adjectives, then D is your best option, but it's not a clean requirement in the context provided.