To solve the quadratic equation \( x^2 - 16x + 64 = 0 \) using the perfect square trinomial pattern, we can recognize that the left-hand side can be rewritten as:
\[ (x - 8)^2 = 0 \]
This is because:
\[ (x - 8)(x - 8) = x^2 - 8x - 8x + 64 = x^2 - 16x + 64 \]
Setting the equation to 0 gives us:
\[ (x - 8)^2 = 0 \]
Now, we take the square root of both sides:
\[ x - 8 = 0 \]
Adding 8 to both sides, we find:
\[ x = 8 \]
Therefore, the solution to the quadratic equation \( x^2 - 16x + 64 = 0 \) is:
\[ \text{Response: } x = 8 \]