To solve the equation
\[ (2x - 5)(x + 4)(x - 8) = 0, \]
we can set each factor equal to zero and solve for \( x \).
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Set \( 2x - 5 = 0 \): \[ 2x = 5 \quad \Rightarrow \quad x = \frac{5}{2}. \]
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Set \( x + 4 = 0 \): \[ x = -4. \]
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Set \( x - 8 = 0 \): \[ x = 8. \]
Now we have the solutions: \[ x = \frac{5}{2}, -4, 8. \]
Thus, the final answer is: \[ \frac{5}{2}, -4, 8. \]