To simplify the expression \(\frac{t^{400}}{t^{100}}\) using the quotient rule of integer exponents, we apply the rule that states:
\[ \frac{a^m}{a^n} = a^{m-n} \]
For your expression:
\[ \frac{t^{400}}{t^{100}} = t^{400 - 100} = t^{300} \]
So, the simplified expression is:
\[ t^{300} \]