To simplify the expression \((1 + 5r)(-3)\), you need to distribute \(-3\) to both terms inside the parentheses:
\[ (1 + 5r)(-3) = 1 \cdot (-3) + 5r \cdot (-3) \]
Calculating each term:
- \(1 \cdot (-3) = -3\)
- \(5r \cdot (-3) = -15r\)
Combining these results gives:
\[ -3 - 15r \]
Thus, the simplified expression is:
\[ \boxed{-3 - 15r} \]