To simplify the expression \( 6(3q−4) + 18−12q−7(4q+5) \), we start by distributing the terms:
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Distribute \(6\) into \( (3q - 4) \): \[ 6(3q) - 6(4) = 18q - 24 \]
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Distribute \(-7\) into \( (4q + 5) \): \[ -7(4q) - 7(5) = -28q - 35 \]
Now substitute these back into the original expression: \[ 18q - 24 + 18 - 12q - 28q - 35 \]
Next, combine like terms for \(q\) and constant terms:
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Combine the \(q\) terms: \[ 18q - 12q - 28q = (18 - 12 - 28)q = -22q \]
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Combine the constant terms: \[ -24 + 18 - 35 = -24 + 18 = -6 \] \[ -6 - 35 = -41 \]
Putting it all together gives: \[ -22q - 41 \]
Thus, the simplified expression is: \[ \boxed{-22q - 41} \]