To simplify the expression \(-5 + \frac{3}{4}(8h + 12) - 10h\), we will follow the order of operations:
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First, distribute \(\frac{3}{4}\) into the parentheses: \[ \frac{3}{4}(8h + 12) = \frac{3}{4} \cdot 8h + \frac{3}{4} \cdot 12 = 6h + 9. \]
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Now, substitute back into the expression: \[ -5 + 6h + 9 - 10h. \]
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Combine like terms:
- The \(h\) terms: \(6h - 10h = -4h\)
- The constant terms: \(-5 + 9 = 4\)
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Therefore, combining these results gives us: \[ 4 - 4h. \]
So, the simplified expression is: \[ \boxed{4 - 4h}. \]