To simplify \( \frac{13^{12}}{13^{-10}} \), we can use the property of exponents that states:
\[ \frac{a^m}{a^n} = a^{m-n} \]
Applying this property here:
\[ \frac{13^{12}}{13^{-10}} = 13^{12 - (-10)} = 13^{12 + 10} = 13^{22} \]
So, the simplified form is:
\[ \boxed{13^{22}} \]