The statement that best supports the classification of viruses as nonliving is:
Viruses must infect living host cells in order to reproduce.
This statement highlights that viruses cannot carry out the processes of life, such as reproduction, independently. Instead, they rely on the machinery of a living host cell to replicate, which is a key reason why they are considered nonliving entities.
The other statements indicate characteristics of viruses, but having genetic material, being made of proteins and nucleic acids, and mutating do not, by themselves, support the classification of viruses as nonliving.