S cycle in the cell cycle. Why is this phase necessary for the remainder of the cycle to occur correctly?

1 answer

The S phase, or synthesis phase, of the cell cycle is crucial because it is the stage in which DNA replication occurs. During this phase, each chromosome is duplicated, resulting in two sister chromatids for each chromosome. This is essential for several reasons:

  1. Genetic Consistency: Before a cell divides (either through mitosis or meiosis), it must ensure that both daughter cells receive an identical set of chromosomes. Without the S phase, daughter cells would end up with incomplete or missing genetic information, which could lead to malfunction or disease.

  2. Preparation for Cell Division: The S phase ensures that the cell has the right amount of DNA to successfully distribute to each daughter cell during cell division. If this duplication does not occur, the resulting cells may not function properly due to incorrect genomic content.

  3. Regulation of the Cell Cycle: DNA replication in the S phase activates checkpoints that prevent the cell from progressing to the next phase (G2 and mitosis) until all DNA is accurately replicated and undamaged. This helps maintain genomic stability and prevents errors that could lead to cancerous growth or other issues.

In summary, the S phase is necessary for the accurate and complete replication of the cell's DNA, which is vital for ensuring that the cell cycle can proceed correctly and that daughter cells can function properly after division.