The principles of the Declaration of Independence emphasize equality, unalienable rights, and the consent of the governed. Based on these principles, the facts about slavery in the United States that directly conflict with the Declaration's principles are:
A. Slaves could not vote on the government.
D. Slaves were not paid for their labor.
E. Slaves were not free to pursue their interests.
These options highlight the lack of rights, lack of economic compensation, and absence of personal freedoms that directly contradict the ideals expressed in the excerpt from the Declaration of Independence. Options B and C are related to slavery but do not directly conflict with the principles as outlined.