The pair that would react most easily with each other is:
an element with a high electronegativity and an element with a single valence electron.
This is because an element with high electronegativity is likely to be a nonmetal (like halogens), which tends to attract electrons, while an element with a single valence electron is typically a highly reactive metal (like alkali metals). The metal can easily lose its single electron, and the nonmetal can readily gain that electron, leading to a strong ionic bond.