To calculate the commission from the sale, you can use the following formula:
\[ \text{Commission} = \text{Sale Amount} \times \text{Commission Rate} \]
Here, the sale amount is $250 and the commission rate is 4%, which can be expressed as a decimal (0.04).
Now plug in the values:
\[ \text{Commission} = 250 \times 0.04 = 10 \]
Therefore, the sales commission is $10.