A substitution mutation occurs when one nucleotide is replaced with another in a DNA sequence.
Let's start with the original DNA sequence provided:
Original Sequence:
C G T T A C T G C A A T
G C A A T G A C G T T A
Now, we will look at each of the options to identify the substitution mutation:
-
C G T C T A C T G C A A T
This first line has "T" changed to "C" (C G T C T A C T) (substitution occurred). Second line is also mutated.
(Substitution mutation) -
G C A G A T G A C G T T A
This first line has "A" changed to "G" (G C A G A T...) (substitution occurred), second line is also mutated.
(Substitution mutation) -
C G T G A C T G C A A T
This first line has "T" changed to "G" (C G T G A...) (substitution occurred), second line is also mutated.
(Substitution mutation) -
G C A C T G A C G T T A
This first line has "A" changed to "C". (G C A C T ...) (substitution occurred), second line is also mutated.
(Substitution mutation) -
C G T T A C T G C A A T
This option is identical to the original sequence - no mutations observed.
(No mutation) -
C G T A C T G C A A T
This first line has "T" changed to "A" (C G T A C T ...) (substitution occurred). Second line is the original one.
(Substitution mutation) -
G C A T G A C G T T A
This first line has "A" changed to "T" (G C A T ...) (substitution occurred). Second line is the original one.
(Substitution mutation)
Thus, all options except the last option show a substitution mutation.
If you need one clear example of substitution among them, you can select either:
- C G T C T A C T G C A A T
- G C A G A T G A C G T T A
- C G T G A C T G C A A T
- G C A C T G A C G T T A
- C G T A C T G C A A T
- G C A T G A C G T T A
These all show a substitution mutation within the presented sequences.
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