To determine which definition of "profound" best fits its use in paragraph 4 of "Tell-Tale Heart," I would need to know the context in which it is used in that paragraph. If the paragraph discusses deep insights, intense emotions, or significant implications, it may align with Definitions 1, 2, or 3. If it refers to something situated at a great depth, then Definition 4 would be appropriate.
If you provide the specific sentence or context from paragraph 4, I can help you identify the most fitting definition!