Positive selection of lymphocytes ?

occurs after exposure to a foreign antigen is a type of non- specific defense
requires activation of interferons
prevents autoimmune diseases
selects for lymphocytes that are capable of binding antigens

1 answer

and initiating an immune response, leading to the production of specific antibodies or cytotoxic T cells.

Positive selection of lymphocytes is essential for the proper functioning of the immune system. It ensures that only lymphocytes that are capable of recognizing and responding to foreign antigens are allowed to mature and participate in the immune response. This process involves the presentation of self-antigens to immature lymphocytes, and those lymphocytes that do not bind to these antigens are eliminated through apoptosis.

Furthermore, positive selection plays a crucial role in preventing autoimmune diseases. Autoimmune diseases occur when the immune system attacks its own cells and tissues, mistaking them for foreign invaders. Proper positive selection reduces the chance of autoimmunity by eliminating self-reactive lymphocytes.

In summary, positive selection of lymphocytes is a highly specific and essential process for the proper functioning of the immune system. It ensures that only lymphocytes capable of recognizing and responding to foreign antigens are allowed to mature, preventing the development of autoimmune diseases.
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