The option that would likely achieve the best results for a patient interested in participating in a smoking cessation program is:
C. Counseling and nicotine.
Research has shown that a combination of behavioral counseling and pharmacotherapy (such as nicotine replacement therapy) generally leads to higher rates of quitting compared to either treatment alone. Other medications, such as varenicline, are also effective, but the combination of counseling and nicotine replacement is a well-established approach for enhancing smoking cessation success.