One side strand of a DNA molecule read 3' ATC GAC CAT 5'. What would the complementary strand read?

a
5' ATC GAC CAT 3'
b
5' TAG CTG GTA 3'
c
5' TAG CCG GTA 3'
d
5' ATC CCG GTA 3'

1 answer

To find the complementary strand of the given DNA sequence, you need to pair the bases according to the base pairing rules: A (adenine) pairs with T (thymine), and C (cytosine) pairs with G (guanine).

The provided sequence is: 3' ATC GAC CAT 5'

Complementary base pairing gives:

  • A pairs with T
  • T pairs with A
  • C pairs with G
  • G pairs with C
  • C pairs with G
  • A pairs with T
  • C pairs with G
  • C pairs with G
  • A pairs with T
  • T pairs with A

Now, write the complementary sequence in the 5' to 3' direction (since the complementary strand runs antiparallel to the original strand): 5' TAG CTG GTA 3'

Thus, the correct answer is: b 5' TAG CTG GTA 3'.