Simon Pokagon, as an American Indian leader, would have been most likely to oppose the Dawes Act. The Dawes Act of 1887 aimed to assimilate Native Americans into American society by allotting them individual plots of land and selling off surplus land to non-Native settlers. This legislation undermined tribal sovereignty and communal land ownership, which were central to many Native American cultures and livelihoods. Given Pokagon's emphasis on the loss of homes and the impact of colonization on his people, it is consistent that he would oppose the Dawes Act.
Answer: A) the Dawes Act