The first attempt at colonization, which involved the establishment of Charlesfort by French Huguenots in 1562, was ultimately unsuccessful due to harsh conditions and lack of support from France, leading to its abandonment. Conversely, the second attempt in 1564 led to the establishment of Fort Caroline, which had a more substantial impact on the region, although it too faced challenges and was eventually taken over by the Spanish.
In evaluating which attempt was more successful, one could argue that the second attempt was more significant due to the establishment of a more lasting presence and the development of relationships with the indigenous populations. This attempt ultimately influenced the dynamics of European colonialism in the Southeast.
However, if considering purely survival and lasting settlement, the assertion that the first attempt was more successful because of the creation of Charlesfort holds some merit; yet, it is important to note that it did not last long and lacked substantial support. Overall, the second attempt is often viewed as more impactful despite its eventual downfall.