To multiply the two binomials \( (2x + 5)(2x - 5) \), we can use the difference of squares formula, which states that \( (a+b)(a-b) = a^2 - b^2 \).
Here, let \( a = 2x \) and \( b = 5 \). Thus, we have:
\[ (2x + 5)(2x - 5) = (2x)^2 - (5)^2 \]
Now, calculate each square:
\[ (2x)^2 = 4x^2 \quad \text{and} \quad (5)^2 = 25 \]
Substituting back into the difference of squares formula gives:
\[ 4x^2 - 25 \]
Thus, the product expressed as a polynomial in standard form is:
\[ \boxed{4x^2 - 25} \]