The correct response is:
The vacuole in plant cells is large and often located centrally; the vacuoles in animal cells are much smaller.
In plant cells, the central vacuole serves multiple functions, including storage of nutrients and waste products, maintaining turgor pressure, and playing a role in cell growth. In contrast, animal cells have smaller vacuoles that serve primarily as storage for various substances, such as ions and nutrients, but they are not as prominent or central as those in plant cells.