To find out how many ounces of cheese are in one slice of pizza, we start with the total amount of cheese used for the pizza, which is 16 ounces. The pizza is cut into 8 slices.
To find the amount of cheese per slice, we divide the total ounces of cheese by the number of slices:
\[ \text{Ounces of cheese per slice} = \frac{16 \text{ ounces}}{8 \text{ slices}} = 2 \text{ ounces} \]
So, the correct answer is c. 2 ounces of cheese in one slice of pizza.