Life as we know it depends on the genetic code: a set of codons, each made up of three bases in a DNA sequence and corresponding mRNA sequence, that specifies which of the 20 amino acids will be added to the protein during translation.

Imagine that a prokaryote-like organism has been discovered in the polar ice on Mars. Interestingly, these Martian organisms use the same DNA → RNA → protein system as life on Earth, except that

there are only 2 bases (A and T) in the Martian DNA, and

there are only 17 amino acids found in Martian proteins.
Based on this information, what is the minimum size of a codon for these hypothetical Martian life-forms?
View Available Hint(s)for Part C

2 bases
3 bases
4 bases
5 bases
6 bases
The answer cannot be determined from the information provided

1 answer

To determine the minimum size of a codon for the hypothetical Martian life-forms, we first need to calculate how many unique combinations of codons can be generated with the given number of bases and then match that to the number of amino acids they use.

  1. Number of Bases: The Martian organisms use only 2 bases (A and T).

  2. Number of Amino Acids: There are 17 amino acids.

A codon is defined as a sequence of bases that corresponds to an amino acid. The number of unique codons that can be formed is calculated as \( n^k \), where \( n \) is the number of bases and \( k \) is the length of the codon.

Given:

  • \( n = 2 \) (A and T)
  • \( k \) is the length of the codon we need to determine.

To find the minimum \( k \) such that the number of distinct codons is at least 17, we start calculating:

  • For \( k = 1 \): \( 2^1 = 2 \)
  • For \( k = 2 \): \( 2^2 = 4 \)
  • For \( k = 3 \): \( 2^3 = 8 \)
  • For \( k = 4 \): \( 2^4 = 16 \)
  • For \( k = 5 \): \( 2^5 = 32 \)

From the calculations:

  • At \( k = 4 \) (codon length of 4), there are 16 unique combinations, which is not enough to code for 17 different amino acids.
  • At \( k = 5 \), there are 32 unique combinations, which is more than sufficient to represent the 17 amino acids.

Therefore, the minimum size of a codon for these Martian life-forms is 5 bases.