Let \( x \) be the number of comic books on each shelf initially. Since there are 5 shelves, the total number of comic books can be expressed as:
\[ 5x \]
When Jose's father adds 20 comic books to the bottom shelf, the number of books on that shelf becomes:
\[ x + 20 \]
According to the problem, this shelf now has 125 books. Therefore, we can set up the equation:
\[ x + 20 = 125 \]
To find \( x \), we solve the equation:
\[ x = 125 - 20 \] \[ x = 105 \]
Now that we know there are 105 comic books on each shelf, we can find the total number of comic books in Jose's collection:
\[ 5x = 5 \times 105 = 525 \]
Thus, the total number of books in his collection is:
\[ \boxed{525} \]