The region you're referring to, particularly during the late 18th and early 19th centuries, was generally aligned with the Federalist Party. The Federalists were more supportive of a strong central government and were associated with business and manufacturing interests, which were more prevalent in the northeastern states.
In contrast, the Democratic-Republicans, led by figures like Thomas Jefferson and James Madison, were more aligned with agrarian interests and were mainly supported by rural areas and southern states. They advocated for a weaker central government and more power for the states.
So, in summary, the northeastern states with a growing business and manufacturing economy during that time would be associated with the Federalist Party.