In which of the following scenarios is the offspring most likely to express the genetic condition?

Question

Both parents are a carrier for an autosomal recessive condition. The offspring is a female.
Only the father is a carrier for an X-linked recessive condition. The offspring is a male.
Only the mother is a carrier for an X-linked recessive condition. The offspring is a male.
Only the mother is a carrier for an X-linked recessive condition. The offspring is a female.

Answer 1

Both parents are a carrier for an autosomal recessive condition. The offspring is a female.

In this scenario, if both parents are carriers for an autosomal recessive condition, there is a 25% chance that their offspring (regardless of sex) will inherit two copies of the mutated gene and therefore express the genetic condition.