In the Michaelis-Menten equation, KM = Ks only when the equilibrium assumption is valid. Which of the following conditions would have to be satisfied for Ks to be within 10% of KM?

1. k-1 = 0.9 × k2

2. k2 = 0.09 × k1

3. k2 = 0.9 × k-1

4. k-1 = 9.0 × k1

5. k2 = 0.09 × k-1

IM soo confused on how to do this .....can someone plz help me ? :(