in terms of their nuclei, skeletal muscle fibers are different than most cells in two ways. What are those ways?

Answer 1

Skeletal cells differ from most cells in two ways.
One, they are multinucleate, meaning they have more than one nucleus.

Two, the nuclei of the cells are near the edge rather than the center of the cell.

Answer 2

Skeletal muscle fibers are multinucleate. The nuclei are located just under the sarcolemma, which is the plasma membrane of the muscle fiber.