The correct pair describing how a macromolecule is constructed is:
Protein is made up of amino acids.
The other options are incorrect for the following reasons:
- Nucleic acids are made up of DNA. (This is incorrect because DNA is a type of nucleic acid, not what nucleic acids are made of.)
- Amino acids are made up of protein. (This is incorrect; amino acids are the building blocks of proteins, not the other way around.)
- DNA is made up of nucleic acids. (This is incorrect; DNA itself is a type of nucleic acid and is not made of additional nucleic acids.)
Thus, the only correct statement is that proteins are made up of amino acids.