Im a medical student and i need to evaluate the Association between depression to cardiovascular disease. 1. what Type of Research Studies makes sense to do? 2.Design (Study period, epidemiological approach...) 2. Who are the participants in study and how will be selected? (Selection criteria, sampling) 4. What measurements will be performed? (Definition of exposure, definition of outcome, Confounders) 5. How many individuals should be assessed and how it will be processed the data analysis?