To determine how cardiac output (CO) responds to an increase in oxygen consumption (VO2), we can use the relationship described by the Fick principle, which states:
\[ VO2 = CO \times (CaO2 - CvO2) \]
where:
- \( VO2 \) = oxygen consumption
- \( CO \) = cardiac output
- \( CaO2 \) = arterial oxygen content
- \( CvO2 \) = venous oxygen content
If the oxygen consumption rate increases eight times, the cardiac output will typically need to increase to meet that demand, but it depends on the differences in arterial and venous oxygen content (the oxygen extraction).
In a state of maximum exercise or increased metabolic demand, the body is able to extract more oxygen from the blood, which can mean that the increase in cardiac output might not need to be as great as the increase in oxygen consumption.
Therefore, the cardiac output may increase, but it likely will not need to increase in a one-to-one ratio with the increase in oxygen consumption.
Given this reasoning, the best answer to your question is:
C. less than eight times.