If a person with Down syndrome marries a person without Down syndrome, is it possible for their child not to have Down syndrome?

I assume that there is a 50% chance that they could have a child that will not have down syndrome.

Is this correct?

3 answers

It's very likely that a child with Down Syndrome did not inherit it. Less than 4% of people with this condition have inherited it. Check this article.

http://www.mayoclinic.com/health/down-syndrome/DS00182/DSECTION=causes
thanks so much for the article
You're very welcome.