To identify the vertex of the quadratic function \( y = -10(x + 15)^2 - 18 \), we can observe the equation is in the vertex form of a parabola, which is:
\[ y = a(x - h)^2 + k \]
where \((h, k)\) is the vertex of the parabola.
In the given equation, we can rewrite it to match the standard form:
\[ y = -10(x - (-15))^2 - 18 \]
From this form, we can see that \( h = -15 \) and \( k = -18 \). Therefore, the vertex of the parabola is:
\[ (-15, -18) \]
So the correct response is:
\((-15, -18)\)