I have two questions regarding enthalpy of reactions:

1.) Care must be taken when dissolving NaOH pellets in water because the temp. can rise dramatically. Taking NaOH as system, what can be deduced about the signs of the entropy of system and surroundings?
Am I correct in saying that delta s system is< 0 and delta s surroundings is > 0?
2.)As body temp. is raised, protein structure is changed and no longer functional. Protein denaturation is this process. What can be deduced from this about enthalpy and entropy changes?
Am I correct in saying that the delta h is > 0 and the delta s is < 0?