For your first question about how emphasis is created in the artwork, the responses could depend on the specific artwork you're referring to. However, without more context, it's common for artists to use color to create emphasis by using contrasting colors to draw attention to certain areas of the piece.
For your second question regarding the Principles of Design, the correct response would be how the elements are organized to create a harmonious work of art. The Principles of Design help to arrange and utilize the Elements of Art effectively in a composition.