In eukaryotic DNA replication, a single molecule of eukaryotic DNA (such as a linear chromosome) typically has multiple replication bubbles. This is due to the fact that eukaryotic genomes are large and replication must occur efficiently. Replication begins at specific sites known as origins of replication, and multiple origins can be activated along each chromosome during the S phase of the cell cycle.
Each origin of replication gives rise to a replication bubble, where DNA unwinds and is replicated. The number of replication bubbles depends on the size of the DNA molecule and the specific organism, but it can range from several dozen to over a hundred on a single eukaryotic chromosome during the replication process.
To summarize, a single eukaryotic DNA molecule can have multiple replication bubbles, and the exact number can vary depending on the specific chromosome and the organism.
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